Islet autotransplantation: past, present and future. Chapter II: the role of islet autotransplantation for the treatment of chronic pancreatitis
نویسندگان
چکیده
cGMP Cell Processing Facility, 1450 NW 10th Avenue, #4014, Cell Transplant Center, Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA Diskapi Yildirim Beyazit Egitim ve Arastirma Hastanesi, Endokrinoloji Klinigi, İrfan Baştuğ Caddesi, Yıldırımbeyazıt/Dışkapı, Ankara, Turkey Division of Endocrinology, Diabetes, & Metabolism, Clinical Cell Transplant Program, 1450 NW 10th Avenue, Miller School of Medicine, University of Miami, Miami, FL 33136, USA Division of Cellular Transplant, 1450 NW 10th Avenue, Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA *Author for correspondence: [email protected] January2015January 2015
منابع مشابه
Is Total Pancreatectomy with Islet Autotransplantation A Reasonable Choice for Pediatric Pancreatitis?
Chronic pancreatitis is an emerging and poorly understood disease in childhood. Total pancreatectomy with islet cell autotransplantation is being proposed as a treatment for chronic pancreatitis and recent studies report a more favorable outcome in children compared to adults. Herein, we review the therapeutic alternatives for pediatric chronic pancreatitis, focusing primarily on TP/IAT.
متن کاملTotal pancreatectomy and quality of life.
Intractable pain is one of the main indications for a surgical approach in chronic pancreatitis. In some cases, especially when the main pancreatic duct is not dilated and when other treatment measures have failed, one surgical approach is a total pancreatectomy. A complication of this approach is diabetes and islet autotransplantation has been suggested in recent years as a good option for min...
متن کاملSystematic review of total pancreatectomy and islet autotransplantation for chronic pancreatitis (Br J Surg 2012; 99: 761-766).
BACKGROUND Total pancreatectomy and islet autotransplantation (TP/IAT) is a treatment option in a subset of patients with chronic pancreatitis. A systematic review of the literature was performed to evaluate the outcome of this procedure, with an attempt to ascertain when it is indicated. METHODS MEDLINE (1950 to present), Embase (1980 to present) and the Cochrane Library were searched to ide...
متن کاملTotal pancreatectomy and islet cell autotransplantation: Definitive treatment for chronic pancreatitis.
In appropriately selected patients, total pancreatectomy and islet cell autotransplant controls pain and improves quality of life while often minimizing the development of overt diabetes. Multidisciplinary management and lifelong follow-up help to maximize the benefit of this procedure. This review highlights its history, indications, metabolic outcomes, and future directions.
متن کاملHuman islet isolation and transplantation in chronic pancreatitis using the automated method.
CHRONIC pancreatitis is the most frequent cause of pancreatogenous diabetes mellitus. 1 Pain is the major indication for surgical intervention and is the main complaint in about one third of the patients who undergo surgery.2 The choice of surgical technique is generally dictated by the ductal anomalies and the presence of associated disease.3 Most of the cases that present smallduct pancreatit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2015